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Patent Searching and Data


Title:
NOVEL COMPOUND, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
Document Type and Number:
Japanese Patent JPH02292284
Kind Code:
A
Abstract:

NEW MATERIAL: A compound of formula I {wherein R0 is formula II-IV [wherein R1-R3 are each H, a halogen, a (substituted) 1-6C alkyl, aryl, aralkyl, heterocyclyl, a 1-6C alkoxy, OH, etc.]}.

EXAMPLE: 2-(1-Normon-2-yl)-5-(3-phenylisoxazol-5-yl)oxazole.

USE: An anti-mycoplasmal and antibacterial agent.

PREPARATION: A compound represented by formula V (wherein Z1-Z3 are each H or an OH-protecting group) is reacted with a compound represented by formula VI (wherein M+ is a metal cation; and R4 is an anion stabilizing group which will be optionally eliminated by a β-hydroxyl group to form an olefin), and subjected to subsequent removal, if necessary, of the optional hydroxyl-protecting group to obtain the objective compound.


Inventors:
PIITAA JIYON OOHANRON
GURAHAMU UORUKAA
Application Number:
JP9417090A
Publication Date:
December 03, 1990
Filing Date:
April 11, 1990
Export Citation:
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Assignee:
SMITHKLINE BEECHAM PLC
International Classes:
C07D413/14; (IPC1-7): C07D413/14
Attorney, Agent or Firm:
Masamitsu Akizawa (1 person outside)