Title:
NOVEL COMPOUND, MANUFACTURE AND MEDICINAL COMPOSITION
Document Type and Number:
Japanese Patent JPS62181252
Kind Code:
A
Abstract:
A compound of formula (1) or a pharmaceutically acceptable salt thereof:wherein:R, is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen;R2 and R3 are both hydrogen or together represent a bond;R4 is selected from C1-6 alkyl, phenyl, phenyl-C1-4 alkyl, CORe where R8 is hydroxy, C1-6 alkoxy or NR9R10 where R9 and R10 are independently hydrogen or C1-4 alkyl and CH2OR11 where R11 is hydrogen, C1-4 alkyl or C1-4 alkanoyl;R6 is hydrogen, C1-6 alkyl or phenyl C1-4 alkyl;R6 is phenyl C1-7 alkyl in which the phenyl moiety is optionally substituted by one or two of halogen, ortho-nitro. meta-or para-methoxy, methyl or NR12R13 wherein R12 and R13 are independently hydrogen or C1-6 alkyl or R12 and R13 together are C2-6 polymethylene or the phenyl moiety is 3,4- disubstituted by methylenedioxy or ethylenedioxy; andR7 is hydrogen or C1-4 alkyl, processes for its preparation and its use as a pharmaceutical.
Inventors:
THIELKE DIETRICH (DE)
HOELTJE DAGMAR (DE)
HOELTJE DAGMAR (DE)
Application Number:
JP30756686A
Publication Date:
August 08, 1987
Filing Date:
December 23, 1986
Export Citation:
Assignee:
BEECHAM WUELFING GMBH & CO KG
International Classes:
C07D209/10; A61K31/40; A61K31/403; A61K31/404; A61P9/00; C07D209/16; C07D209/30; C07D209/42; (IPC1-7): A61K31/40; C07D209/10; C07D209/16; C07D209/30
Attorney, Agent or Firm:
Masamitsu Akizawa