Title:
NOVEL NITROCATECHOL DERIVATIVE
Document Type and Number:
Japanese Patent JP2020158391
Kind Code:
A
Abstract:
To provide a novel nitrocatechol derivative or a salt thereof that has catechol-O-methyltransferase inhibitory action and dopa decarboxylase inhibitory action and to provide a pharmaceutical composition containing the same derivative or the salt thereof.SOLUTION: A compound represented by formula (1) or a pharmaceutically acceptable salt thereof and a pharmaceutical composition including the same compound or the salt thereof are provided. [A ring A represents 3 to 6 heterocyclic compounds represented by oxadiazole or the like; Q1 to Q6 are each independently C, N, S or O; X, Y and Z are each independently a single bond, C, O, N or S; R1, R2 and R11 are each independently H or alkylcarbonyl; R3 is H, halogen or haloalkyl; R4 is H, halogen or alkyl; R5 to R10 are each independently H, halogen, alkyl or cyano; and n is an integer of 0 to 3.]SELECTED DRAWING: None
Inventors:
KATO HIROSHIGE
INOUE TSUTOMU
NAGAYAMA SACHIHO
TOKUYAMA TATSUMITSU
KOBASHI SEIICHI
MATSUMOTO KOJI
HOSOYA TAKUJI
INOUE TSUTOMU
NAGAYAMA SACHIHO
TOKUYAMA TATSUMITSU
KOBASHI SEIICHI
MATSUMOTO KOJI
HOSOYA TAKUJI
Application Number:
JP2017132272A
Publication Date:
October 01, 2020
Filing Date:
June 13, 2017
Export Citation:
Assignee:
FUJIYAKUHIN CO LTD
International Classes:
C07D271/06; A61K31/41; A61K31/415; A61K31/417; A61K31/4192; A61K31/4196; A61K31/42; A61K31/421; A61K31/4245; A61K31/426; A61K31/433; A61K31/4439; A61K31/454; A61K31/501; A61P25/16; A61P43/00; C07D231/12; C07D233/64; C07D249/06; C07D249/08; C07D257/04; C07D261/04; C07D263/32; C07D271/10; C07D277/28; C07D277/56; C07D285/08; C07D401/04; C07D401/06; C07D403/04; C07D405/04; C07D409/04; C07D413/06; C07D413/08