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Patent Searching and Data


Title:
NOVEL PLATINUM COMPLEX AND PRODUCTION THEREOF
Document Type and Number:
Japanese Patent JPS62238296
Kind Code:
A
Abstract:

NEW MATERIAL:A platinum complex expressed by formula I and optically active isomer thereof.

USE: A synthetic intermediate for carcinostatic agents.

PREPARATION: A platinum (II) potassium chloride expressed by the formula K2PtCl4 and potassium thiocyanate expressed by the formula KSCN in a molar amount of preferably 4 times based on the platinum (II) potassium chloride are dissolved in water and reacted at 0W100°C, preferably 20W80°C, normally for 0.5W5hr while stirring to give a reaction product. 2-Aminomethylpyrrolidine expressed by formula II or an optically active isomer thereof in an amount equimolar with the above-mentioned platinum compound and the reaction mixture is stirred, preferably at 0W100°C for 0.5W10hr to collect the resultant solid by filtration. The solid is then washed with water and dried at 0W80°C under reduced pressure.


Inventors:
HONDA NARIMITSU
MORIKAWA KAZUMI
Application Number:
JP7985986A
Publication Date:
October 19, 1987
Filing Date:
April 07, 1986
Export Citation:
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Assignee:
CHUGAI PHARMACEUTICAL CO LTD
International Classes:
C07F15/00; (IPC1-7): C07F15/00