Title:
OPTIMIZED Fc VARIANT
Document Type and Number:
Japanese Patent JP2011188869
Kind Code:
A
Abstract:
To provide Fc variants optimized for a number of therapeutically relevant properties.
The present invention relates to the optimized Fc variants, methods for their generation, Fc polypeptides comprising the optimized Fc variants, and methods for using the optimized Fc variants.
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Inventors:
LAZAR GREGORY ALAN
DANG WEI
DESJARLAIS JOHN R
KARKI SHER BAHADUR
VAFA OMID
HAYES ROBERT
DANG WEI
DESJARLAIS JOHN R
KARKI SHER BAHADUR
VAFA OMID
HAYES ROBERT
Application Number:
JP2011136557A
Publication Date:
September 29, 2011
Filing Date:
June 20, 2011
Export Citation:
Assignee:
XENCOR INC
International Classes:
C12N15/09; A61K39/395; C07K16/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
Domestic Patent References:
JP4578467B2 | 2010-11-10 | |||
JP4578467B2 | 2010-11-10 |
Foreign References:
WO2004029207A2 | 2004-04-08 |
Other References:
JPN6010061806; Current pharmaceutical biotechnology. 2002, Vol.3, No.3, p.237-56
JPN6010061805; The Journal of biological chemistry. 2001, Vol.276, No.9, p.6591-6604
JPN6010061805; The Journal of biological chemistry. 2001, Vol.276, No.9, p.6591-6604
Attorney, Agent or Firm:
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Atsushi Hakoda
Kenji Asai