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Title:
OLIGODEOXYNUCLEOTIDE AND IMMUNOMODULATING AGENT UTILIZING THE SAME
Document Type and Number:
Japanese Patent JP2006325540
Kind Code:
A
Abstract:

To provide a highly safe oligodeoxynucleotide while having high activity as an immunomodulating agent.

The oligodeoxynucleotide comprises a base sequence represented by formula(I):5'-ACTTTCGTTTTCTGCGTCAA-3'. An immunomodulating agent comprising the above oligodeoxynucleotide as active ingredient is provided. A method for producing the above oligodeoxynucleotide is also provided, being characterized by comprising selecting a DNA fragment having the mitogen activity on mouse- and human-derived B lymphocytes from the genomic DNA of microorganisms belonging to the genus Lactobacillus rhamnosus.


Inventors:
SAITO TADAO
KITAZAWA HARUKI
KA TAMOTSU
HOSODA MASATAKA
MORITA HIROTSUGU
Application Number:
JP2005157224A
Publication Date:
December 07, 2006
Filing Date:
May 30, 2005
Export Citation:
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Assignee:
TAKANASHI MILK PRODUCTS CO LTD
UNIV TOHOKU
International Classes:
C12N15/09; A61K31/7088; A61K39/00; A61P29/00; A61P31/00; A61P35/00; A61P37/02; A61P37/08
Other References:
JPN6010069434, Cellular Microbiology, 2005, vol.7 no.3, pp.403−414
Attorney, Agent or Firm:
Nobuo Ono