Title:
ORAL DOSAGE FORM COMPRISING THERAPEUTIC AGENT AND ADVERSE-EFFECT AGENT
Document Type and Number:
Japanese Patent JP2013189447
Kind Code:
A
Abstract:
To provide an oral dosage form containing a first composition and a second composition.
A first composition comprises an effective amount of a therapeutic agent and a second composition comprises an effective amount of an adverse-effect agent. The adverse-effect agent is covered with a coating that is substantially insoluble in the gastrointestinal tract. In one embodiment, the adverse-effect agent is coated with an outer base-soluble layer and an inner acid-soluble layer. The therapeutic agent can be uncoated or can be coated with a coating having an outer acid-soluble layer and an inner base-soluble layer. The dosage form discourages administration of the therapeutic agent by other than oral administration.
Inventors:
WRIGHT CURTIS IV
CARPANZO ANTHONY E
CARPANZO ANTHONY E
Application Number:
JP2013101285A
Publication Date:
September 26, 2013
Filing Date:
May 13, 2013
Export Citation:
Assignee:
EURO CELTIQUE SA
International Classes:
A61K9/16; A61K9/20; A61K9/28; A61K9/30; A61K9/50; A61K9/54; A61K31/485; A61K31/515; A61K31/5513; A61K45/06; A61K47/32; A61P25/04; A61P43/00
Domestic Patent References:
| JP2009132711A | 2009-06-18 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
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