Title:
【発明の名称】光学活性脂肪族カルボン酸の製造
Document Type and Number:
Japanese Patent JPH10512888
Kind Code:
A
Abstract:
A process for the separation of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process comprises i) forming a diastereomeric salt by reaction comprising said racemic mixture of a C1 to C6 linear or branched aliphatic carboxylic acid and an amount of a chiral organic base sufficient to react with one of the enantiomers of the racemic mixture; ii) precipitating from the reaction solution formed in step i) the diastereomeric salt; iii) separating said precipitated diastereomeric salt; iv) decomposing the salt into its enantiomeric component and its organic base component; and v) isolating a substantially pure enantiomer from said decomposed salt.
Inventors:
Patel, Day Park Earl
Ramachi Yandran, Ben Kataraman
Ramachi Yandran, Ben Kataraman
Application Number:
JP52299596A
Publication Date:
December 08, 1998
Filing Date:
January 24, 1996
Export Citation:
Assignee:
Albemarle Corporation
International Classes:
C07B57/00; C07C51/487; C07C57/30; C07C57/58; C07C59/64; (IPC1-7): C07C51/487; C07C57/30; C07C57/58; C07C59/64
Attorney, Agent or Firm:
Heiyoshi Odashima
Previous Patent: （５−カルボキサミドまたは５−フルオロ）−（２’，３’−不飽和また...
Next Patent: 機能不全性子宮出血を治療する医薬を製造するためのプロゲステロンアン...
Next Patent: 機能不全性子宮出血を治療する医薬を製造するためのプロゲステロンアン...