Title:
パーキン基質およびアッセイ
Document Type and Number:
Japanese Patent JP2010527614
Kind Code:
A
Abstract:
The invention provides in vitro, ex vivo, and in vivo assays for Parkin activity, in which Parkin-mediated ubiquitination of a Sept4 protein is measured. The assays may be used to screen for agents that modulate Parkin protein ligase activity.
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Inventors:
Ji Young Sung, The Yenifar A
Cutcliffe, Colleen Tsui
Cutcliffe, Colleen Tsui
Application Number:
JP2010509525A
Publication Date:
August 19, 2010
Filing Date:
May 21, 2008
Export Citation:
Assignee:
Elan Fuharma International Limited
International Classes:
C12Q1/48; C12Q1/02; G01N33/15; G01N33/50; C12N15/09
Attorney, Agent or Firm:
Patent business corporation Odashima patent office