Title:
PENETRATION PROMOTOR FOR TRANSDERMAL ADMINISTRATION OF GENERAL DRUG
Document Type and Number:
Japanese Patent JPS63150230
Kind Code:
A
Abstract:
This invention relates to a method for administering systemically active agents including therapeutic agents through the skin or mucosal membranes of humans and animals in a transdermal device or formulation comprising topically administering with said systemic agent an effective amount of a membrane penetration enhancer having the structural formula wherein each X, Y and Z may represent oxygen, sulfur or two hydrogen atoms, provided however that, when Z represents two hydrogen atoms, both X and Y represent oxygen or sulfur and when Z represents oxygen or sulfur at least one of X and Y must represent oxygen or sulfur; m is 2-6; R' is H or a lower alkyl group having 1-4 carbon atoms; n is 0-16 and R is -CH3, wherein R'' is H or halogen. y
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Inventors:
GEBUOOKU MINASUKANIAN
JIEEMUSU BUANOORUDEN PETSUKU
JIEEMUSU BUANOORUDEN PETSUKU
Application Number:
JP29309087A
Publication Date:
June 22, 1988
Filing Date:
November 19, 1987
Export Citation:
Assignee:
NELSON RES & DEV
International Classes:
A61K47/00; A61K47/06; A61K47/22; C07D211/90; C07D223/10; C07D223/06; C07D225/02; (IPC1-7): A61K47/00; C07D211/90; C07D223/06; C07D223/10; C07D225/02
Attorney, Agent or Firm:
Kyozo Yuasa (4 outside)
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