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Patent Searching and Data


Title:
PEPTIDE RELATING TO EXOSPORIUM PROTEIN OF E.COLI
Document Type and Number:
Japanese Patent JPS63139197
Kind Code:
A
Abstract:

NEW MATERIAL:The compound of formula IWIV or its salt.

USE: Hapten for the preparation of antibody for immunoglobulin therapy and an antigen composition for E.coli vaccine.

PREPARATION: The peptide of formula IWIV can be produced e.g. by (1) bonding a C-terminal amino acid to a chloromethylated styrene-divinylbenzene copolymer resin, (2) coupling the resin successively with amino acids having protected amino group according to the amino acid sequence of the objective peptide in the presence of a condensation agent, (3) removing the amino-protecting group, (4) repeating the steps (2) and (3) to obtain a peptide resin and (5) separating peptide from the resin and eliminating protective groups from all functional groups.


Inventors:
KAI HIROYUKI
NOGUCHI HIROSHI
Application Number:
JP28529086A
Publication Date:
June 10, 1988
Filing Date:
November 28, 1986
Export Citation:
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Assignee:
SUMITOMO PHARMA
SUMITOMO CHEMICAL CO
International Classes:
A61K39/108; C07K7/06; C07K7/08; C07K14/195; C07K14/41; C07K14/705; (IPC1-7): A61K39/108; C07K7/06; C07K7/08; C07K99/00
Attorney, Agent or Firm:
Takashima Hajime