To obtain a new physilogically active peptide, comprising a short peptide, containing a specific amino acid sequence and having cell adhesion inhibiting activities and a specific value or below of the number of amino acids, capable of inhibiting the adhesion of eliminated cancer cells and useful as a cancer metastatic suppressant, etc.

This new physiologically active peptide contains an amino acid sequence described in the formula, has cell adhesion inhibiting activities and further ≤30 number of amino acids. The peptide can be applied to research and treatment of various diseases concerned with the cell adhesion. Since the peptide is a short one, the synthesis, handling, etc., thereof are readily carried out. Since the inhibition of the adhesion of eliminated cancer cells is manifested, the peptide is useful as a suppressant, etc., for cancer metastasis. The physiologically active peptide is obtained by synthesizing an amino acid sequence containing an amino acid sequence represented by the formula of the 1848th to the 1855th sites in fibronectin according to a chemical synthetic method such as a solid-phase synthetic method using a peptide synthesizer, etc., or a gene recombination technique for inserting a DNA sequence capable of coding the amino acid sequence into a plasmid vector, transforming a microorganism such as Escherichia coli and expressing the gene.