Title:
メラノコルチン-4受容体作働薬としてのピペラジン尿素誘導体
Document Type and Number:
Japanese Patent JP2006505531
Kind Code:
A
Abstract:
Certain novel piperazine urea derivatives are agonists of the human melanocortin-4 receptor (MC-4R) and, in particular, are receptor-subtype selective agonists of MC-4R. They are useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity and diabetes.
Inventors:
Bakshi, Raman Kumar
Rabbi Pee, Nargand
Paradki, Brenda El
Park, Min Kei
Ye, Chishi Yun
Rabbi Pee, Nargand
Paradki, Brenda El
Park, Min Kei
Ye, Chishi Yun
Application Number:
JP2004536116A
Publication Date:
February 16, 2006
Filing Date:
September 05, 2003
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D401/12; A61K31/496; A61K31/4985; A61K31/4995; A61K31/551; A61K45/00; A61P1/04; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/00; A61P7/00; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P11/00; A61P15/00; A61P19/02; A61P19/06; A61P29/00; A61P35/00; A61P43/00; C07D211/62; C07D401/14; C07D403/12; C07D405/14; C07D417/14; C07D471/04; C07D487/04; C07D487/08
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura