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Title:
ピペリジニルおよびN-アミジノピペリジニル誘導体
Document Type and Number:
Japanese Patent JP4495339
Kind Code:
B2
Abstract:
This invention is directed to a compound of formula I which is useful for inhibiting the activity of Factor Xa, by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.

Inventors:
Scott I Klein
Kevin Earl Gatin
Application Number:
JP2000537853A
Publication Date:
July 07, 2010
Filing Date:
March 22, 1999
Export Citation:
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Assignee:
Aventis Pharmaceuticals Incorporated
International Classes:
C07D211/34; A01N43/40; C07D211/70; A61K31/195; A61K31/405; A61K31/415; A61K31/4172; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4427; A61K31/4433; A61K31/445; A61K31/4462; A61K31/4465; A61K31/454; A61K31/4545; A61K31/47; A61P7/02; A61P9/10; C07D209/18; C07D211/00; C07D211/26; C07D211/28; C07D211/32; C07D211/68; C07D233/54; C07D233/64; C07D401/10; C07D401/12; C07D409/04; C07D409/14; A61K31/4535
Domestic Patent References:
JP11513686A
JP8269001A
JP6506200A
JP9504535A
JP10510539A
JP11512722A
Attorney, Agent or Firm:
Junji Yuda
Chika Takagi
Kosuke Nishimura