Title:
Piperidinyl Naphthyl acetic acid
Document Type and Number:
Japanese Patent JP6154397
Kind Code:
B2
Abstract:
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Inventors:
Pharoosnia, Fariburus
Lynn, Thai-Ann
Mart, eric
Sidri, Atchusarao
Seo, Sung-Saw
Tilly, Jefferson Wright
Lynn, Thai-Ann
Mart, eric
Sidri, Atchusarao
Seo, Sung-Saw
Tilly, Jefferson Wright
Application Number:
JP2014546433A
Publication Date:
June 28, 2017
Filing Date:
December 10, 2012
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D211/96; A61K31/451; A61K31/454; A61K31/4545; A61P11/00; A61P11/06; A61P37/08; C07D211/34; C07D401/12
Domestic Patent References:
JP2012508270A | ||||
JP2009161552A | ||||
JP2012508714A | ||||
JP2009539881A |
Foreign References:
WO2010045276A1 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Toshio Miyake
Akio Shibata
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Keiko Morita
Hajime Tsukuni
Yasuo Yanagibashi
Toshio Miyake
Akio Shibata
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Keiko Morita