Title:
ポリヌクレオチド配列決定法
Document Type and Number:
Japanese Patent JP4094961
Kind Code:
B2
Abstract:
Methods for determining the sequence of a polynucleotide comprising the steps of (i) contacting a polynucleotide processive enzyme immobilised in a fixed position, with a target polynucleotide under conditions sufficient to induce enzyme activity; (ii) detecting an effect consequent on the interaction of the enzyme and the polynucleotide, wherein the effect is detected by measurement of a non-linear optical signal or a linear signal coupled to a non-linear signal.
Inventors:
Daniel Henry Densham
Application Number:
JP2002591533A
Publication Date:
June 04, 2008
Filing Date:
May 20, 2002
Export Citation:
Assignee:
MEDICAL BIOSYSTEMS LTD.
International Classes:
C12Q1/68; G01N21/65; C12M1/34; C12N11/00; C12N15/09; C12Q1/48; C12Q1/6869; G01N21/27; G01Q60/06; G01Q60/18; G01Q60/24; G01Q80/00
Domestic Patent References:
| JP2004530105A | ||||
| JP2004521323A |
Foreign References:
| WO2001025480A1 |
Other References:
Science,1998年,Vol.282,p.1516-1519
Science,1998年,Vol.281,p.363-365
Science,1998年,Vol.281,p.363-365
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Hiroshi Yamazaki