To obtain a preparation for external use for skin, providing excellent improving and preventing activities against not only simple roughened skin but also the roughened skin associated with drying skin disease or the like represented by atopic dermatosis and housewives eczema by using a heparin analogue in combination with urea.

This preparation for external use for skin contains (A) a heparin analogue and (B) urea. For example, the proportion of the formulated component A is 0.01-5 wt.% and that of the component B is 1-25 wt.% based on the whole preparation. The ratio of the formulated components A to B is preferably (1:1000)-(1:1). Further, an antiinflammatory agent such as glycyrrhetic acid in the proportion of 0.1-5 wt.%, an antihistamic agent such as diphenhydramine in the proportion of 0.1-2 wt.%, a local anesthetic such as lidocaine in the proportion of 0.1-2 wt.%, a microbicide such as chlorhexidine hydrochloride in the proportion of 0.05-1 wt.%, and vitamins such as tocopherol in the proportion of 0.05-3 wt.% are preferably formulated therewith.