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Title:
PRODRUG OF DONEPEZIL HYDROCHLORIDE WHICH IS THERAPEUTIC AGENT FOR ALZHEIMER TYPE DEMENTIA
Document Type and Number:
Japanese Patent JP2008280248
Kind Code:
A
Abstract:

To provide a compound expectable of remission and reduction of adverse effects such as vomiting, diarrhea and nightmare rarely observed after administration of donepezil hydrochloride.

The compound is represented by the general formula [wherein, R represents an optionally substituted 1-6C alkyl group, a carbamoyl group optionally substituted with one or two 1-6C alkyl groups, an aryloxycarbonyl group optionally substituted with one to three substituents, a 2-6C alkanoyl group optionally substituted with one to three substituents or an optionally substituted arylcarbonyl group; and n represents an integer of 0 or 1] or a pharmaceutically acceptable salt thereof.


Inventors:
IIMURA YOICHI
MATSUI KENJI
Application Number:
JP2005319382A
Publication Date:
November 20, 2008
Filing Date:
November 02, 2005
Export Citation:
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Assignee:
EISAI R&D MAN CO LTD
International Classes:
C07D211/22; A61K31/445; A61P25/28; A61P43/00; C07D211/94



 
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