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Title:
PRODUCTION OF 2,3-DIHYDROXYPROPYL-2-(1-OXOALKYL) AMINO-2-DEOXYGLUCOPYRANOSIDE AND ITS USE
Document Type and Number:
Japanese Patent JP2804257
Kind Code:
B2
Abstract:

PROBLEM TO BE SOLVED: To obtain the subject new compound useful for a detergent, a cosmetic composition, etc., as a neutral surfactant free from toxicity and irritation, by acylating glucose amine chlorohydrate and reacting the acylated compound with glycerol in the presence of an acid catalyst.
SOLUTION: This new 2,3-dihydroxypropyl-2-(1-oxoalkyl)amino-2 deoxyglucopyranoside of the formula (R is a saturated or an unsaturated 5-21C alkyl) and is useful for a determent and a cosmetic composition as a neutral surfactant having no toxicity and no irritation to skin and mucosa and not harmful to environment. The compound is obtained by reacting glucose amine chlorohydrate with a 6-22C acid chloride (e.g. octylic acid chloride) in the molar ratio of the acid chloride/glucose amine chlorohydrate of 0.7-1.3 to give an N-acyl glucose amine and then reacting this compound with glycerol in the presence of an acid catalyst (e.g. methanesulfonic acid).


Inventors:
Serge Petit
Daniel Bernard
Henri-Jean Copan
Application Number:
JP29758496A
Publication Date:
September 24, 1998
Filing Date:
October 18, 1996
Export Citation:
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Assignee:
Seca Society Anonym
Elf Atochem Society Anonymous
International Classes:
A61K8/00; A61K8/60; A61Q5/00; A61Q5/02; A61Q5/12; A61Q19/10; B01J31/02; B01J31/10; C07B61/00; C07H13/04; C07H15/04; C07H15/12; C11D1/52; C11D1/66; C11D1/68; (IPC1-7): C07H15/04; A61K7/06; A61K7/075; A61K7/50; B01J31/02; B01J31/10; C11D1/68
Attorney, Agent or Firm:
Takashi Koshiba (1 person outside)