To produce endotropine without accompanying danger of fire and explosion.

This method for producing endotropine comprises reducing tropanone with hydrogen activated by catalytic action of Raney nickel or Raney copper. In the method, tropanone and hydrogen are exposed to turbulent flow having 1,000 to 1,500 rpm in a closed system in an aqueous suspension in which Raney nickel or Raney copper is suspended at ordinary temperature and normal pressure. Thereby, reaction occurs smoothly and the desired endo compound is stereoselectively produced. The method is free from danger of fire and explosion, because over pressure and any organic solvent conventionally used are not used.