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Title:
PRODUCTION OF MULTI-HYDROPHILIC GROUP TYPE N-LONG CHAIN ACYLCARBOXYLIC ACID OR ITS SALT
Document Type and Number:
Japanese Patent JPH09227481
Kind Code:
A
Abstract:

To profitably obtain the subject compound free from the deterioration of color tone due to preservation and useful for cosmetics, perfumeries such as shampoos, etc., by reacting a specific multi-hydrophilic group-type amino acid (salt), etc., with an acid halide and subsequently treating the reaction solution with a reducing agent.

This method for producing a multi-hydrophilic group type N-long chain acylcarboxylic acid or its salt comprises reacting (A) a compound of formula I [R1 is a 1-3C (branched) alkylene; Y is a group of the formula: COOM (M is H, a cation), a group of the formula: OSO3M, a group of the component: OPO(OM)2, etc.; (m) is 1-3] with (B) a compound of the formula: R2COX [R2 is a 5-21C (branched) alkyl, alkenyl, hydroxyalkyl; X is a halogen] and, if necessary, subsequently exchanging the salt, or reacting a compound of formula II with the component B, hydrolyzlng the obtained compound and, if necessary, exchanging the salt, and subsequently treating the reaction solution containing a compound of formula III with (D) a reducing agent such as sodium borohydride or sodium sulfite e.g. in an amount of 50ppm to 5wt.% based on the theoretical amount of the compound of formula III at a pH of 8-14.


Inventors:
ABE HIDEYUKI
MIZUSHIMA YOUSEN
FUJIO AKIRA
Application Number:
JP4268896A
Publication Date:
September 02, 1997
Filing Date:
February 29, 1996
Export Citation:
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Assignee:
KAO CORP
International Classes:
A61K8/30; A61K8/00; A61K8/44; A61Q5/02; C07C231/02; C07C233/47; C07C233/49; C07C235/08; C07C303/22; C07C303/24; C07C305/06; C07C309/15; C07F9/09; C11D1/10; C11D1/20; C11D1/34; (IPC1-7): C07C233/47; A61K7/00; A61K7/075; C07C231/02; C07C233/49; C07C235/08; C07C303/22; C07C303/24; C07C305/06; C07C309/15; C07F9/09; C11D1/10; C11D1/20; C11D1/34
Attorney, Agent or Firm:
Kaoru Furuya (3 outside)