PRODUCTION OF NNGLYCOSYL DERIVATIVE OF POLYENEMACRORIDE

Title:

PRODUCTION OF NNGLYCOSYL DERIVATIVE OF POLYENEMACRORIDE

Document Type and Number:

Japanese Patent JPS52131594

Kind Code:

A

Abstract:

The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the reaction medium by means of water or an aqueous solution of an inorganic salt, purified by crystallisation from a higher alcohol, and optionally converted into a salt.

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Inventors:

REONARUDO FUARUKOUSUKI
ZUZANNA KOUSHIKU GINDEIFUA
ZOFUIA PUOSHIENITSUKU
YAN JIERINSUKI
HARINA DAARIGU
IEJIYUI GOORITSUKU
EWA YAKOBUSU
PAUEI KOUOJIECHIETSUKU
ERIJIBIETA BIRETSUCHI
DANUUTA ROSHIRITSUKU

Application Number:

JP4671377A

Publication Date:

November 04, 1977

Filing Date:

April 22, 1977

Export Citation:

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Assignee:

POLITECHNIKA GDANSKA
INST PRZEMYSLU FARMACEUTIC

International Classes:

A61K31/7042; A61K31/7048; A61K31/70; A61K31/715; A61P31/04; C07H17/08; (IPC1-7): A61K31/715; C07H17/08

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