PRODUCTION OF NOVEL STEROID

Title:

PRODUCTION OF NOVEL STEROID

Document Type and Number:

Japanese Patent JPS51125059

Kind Code:

A

Abstract:

17 alpha ,21-Diesters of 17 alpha ,21-dihydroxysteroids of the pregnane series corresponding to the formula I in which the symbols X, Y, R<1> and R<2> have the meaning stated in Claim 1 are prepared by reacting a compound which has the group -CH2OCO(CH2)nZ in position 21, where Z is a substituent which can easily be replaced, with a compound of the formula H-NR<3>R<4>. The compounds are distinguished not only by a good topical antiinflammatory effect but also by an excellent systemic antiinflammatory effect.

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Inventors:

GOODON HANREE FUIRITSUPUSU
DONARUDO KEISU BARANSU
NIOORU GARUBUREISU UEA

Application Number:

JP9213775A

Publication Date:

November 01, 1976

Filing Date:

July 30, 1975

Export Citation:

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Assignee:

GLAXO LAB LTD

International Classes:

C07J5/00; C07J41/00; C07J43/00; (IPC1-7): A61K31/57; A61K31/58; C07J41/00; C07J43/00

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