PURPOSE: To obtain the title compound useful as a ferroelectric liquid crystal compound or an intermediate thereof in a high reaction rate, by reacting a specific halide with an optically active catalyst in the presence of a catalyst.
CONSTITUTION: A halide shown by formula I (R1 is 1-20C alkyl; Y is O, COO or OCO; Ar is group shown by formula II to formula V; Z is Br or I; m is 0 or 1) such as 2-(4-bromophenyl)-5-decyloxypyrimidine is reacted with a com pound shown by formula VI (R2 is H, 1-20C alkyl, 2-20C alkoxyalkyl, etc.; X is H or F; n is 0-10; * is asymmetric carbon) such as (-)-2-acetoxy-3-butene in the presence of a metal catalyst (e.g. Pd-based or Ni-based catalyst) and a basic compound (e.g. alkali metal carbonate) at 100-150°C to give a compound shown by formula VII such as (-)-2-[4-(3-acetoxy-1-butenyl)phenyl]-5- decyloxypyrimidine.
TODA SHOJI
KURIMOTO ISAO
MINAMII MASAYOSHI
