Title:
PRODUCTION OF STABLE S-ADENOSYL-L-METHIONINE SALT
Document Type and Number:
Japanese Patent JPS6070097
Kind Code:
A
Abstract:
A process is described for the large-scale industrial production of any stable SAMe salt at very high purity and with a yield of about 90% or more. The new process is characterized by the following basic operations: (a) production of yeast containing 12-20 g/kg of SAMe, (b) cell lysis and recovery of the SAMe-rich lysate, (c) ultrafiltration of the lysate, (d) passage through weak acid ion exchange resin, (e) passage through absorption resin, (f) concentration by reverse osmosis, (g) spray-drying the concentrated aqueous solution of SAMe salt.
Inventors:
GENNARI FEDERICO (IT)
Application Number:
JP17532684A
Publication Date:
April 20, 1985
Filing Date:
August 24, 1984
Export Citation:
Assignee:
BIORESEARCH SPA (IT)
International Classes:
C07H19/16; C07H19/167; C12P19/40; (IPC1-7): C12P19/40
Attorney, Agent or Firm:
Takao Minami