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Title:
セラミックヒドロキシアパタイトクロマトグラフィーを使用する酸性タンパク質の精製
Document Type and Number:
Japanese Patent JP5793080
Kind Code:
B2
Abstract:
The present invention provides a method of removing product-related inactive or partially active species, high molecular weight aggregates, as well as other process-related impurities from preparations of acidic proteins by using ceramic hydroxyapatite chromatography.

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Inventors:
Shujun Sun
In Luo
Priscilla Jennings
Application Number:
JP2011534754A
Publication Date:
October 14, 2015
Filing Date:
October 29, 2009
Export Citation:
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Assignee:
Weiss LRC
International Classes:
C07K1/16; A61K38/00; A61K39/395; A61K47/42; C07K14/715; C07K14/735; C07K16/00; C07K19/00; C12P21/02; C12P21/08
Domestic Patent References:
JP10215875A
JP8333387A
JP2005519032A
JP2007532477A
JP2008538181A
Other References:
Methods in Enzymology,1990年,Vol.182,p.329-339
Attorney, Agent or Firm:
Noh four
High Hoji Koji
Junko Miyazawa
Maki Sato



 
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