Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PYRAZOLE DERIVATIVE MODULATOR OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL AND METHOD FOR TREATMENT OF NON-SMALL CELL LUNG CANCER
Document Type and Number:
Japanese Patent JP2016028037
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide novel calcium release-activated calcium (CRAC) channel inhibitors.SOLUTION: The present invention provides a compound represented by the following formula, or a tautomer, a prodrug, an N-oxide, a pharmacologically acceptable ester or a pharmacologically acceptable salt thereof (where, ring Hy is an optionally substituted, 1,2-diazole ring; ring Ar is a benzene ring, a pyridine ring or the like; L1 and L2 together represent -NH-C(=O)-, -C(=O)NH- or the like; A is not present or represents an alkylene group or the like; Cy is a bicyclic ring selected from a substituted/unsubstituted cycloalkyl group, a substituted/unsubstituted heterocyclyl, a substituted/unsubstituted aryl and a substituted/unsubstituted heteroaryl).SELECTED DRAWING: None

Inventors:
MEYYAPPAN MUTHUPPALANIAPPAN
SRIKANT VISWANADHA
KANTHIKIRAN VS VARANSI
GAYATRI SWAROOP MERIKAPUDI
SWAROOP KUMAR V S VAKKALANKA
Application Number:
JP2015160031A
Publication Date:
February 25, 2016
Filing Date:
August 14, 2015
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
RHIZEN PHARMACEUTICALS SA
International Classes:
C07D401/12; C07D401/14; C07D403/12; C07D471/04; C07D487/04
Domestic Patent References:
JP2002516909A2002-06-11
JPH11240832A1999-09-07
JP2000256358A2000-09-19
Foreign References:
US20010044445A12001-11-22
Other References:
"Registry No. 1174838-72-2 (Entered STN: 21 Aug 2009)", DATABASE REGISTRY [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014002673
Attorney, Agent or Firm:
Taro Yaguchi



 
Previous Patent: NOVEL ANTI-INFLAMMATORY AGENTS

Next Patent: METHOD FOR PRODUCING (1S, 4R)-2-OXA-3-AZABICYCLO[2.2.1]HEPT-5-ENE