Title:
酵素触媒作用アシル化による1級及び2級アミンのラセミ分割
Document Type and Number:
Japanese Patent JP3594602
Kind Code:
B2
Abstract:
PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.
Inventors:
Fleethelm Balken Hall
Bernhard Hauer
Wolfgang Rattner
Uwe Pressler
Christoph Nubling
Bernhard Hauer
Wolfgang Rattner
Uwe Pressler
Christoph Nubling
Application Number:
JP50954595A
Publication Date:
December 02, 2004
Filing Date:
September 16, 1994
Export Citation:
Assignee:
BASF Aktiengesellschaft
International Classes:
C12P13/02; C12P41/00; C12R1/38; (IPC1-7): C12P13/02; C12P41/00
Domestic Patent References:
| JP3191797A | ||||
| JP4505258A | ||||
| JP4126096A | ||||
| JP5339222A | ||||
| JP6269294A |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel