Title:
ランチビオティックの精製法
Document Type and Number:
Japanese Patent JP2006501854
Kind Code:
A
Abstract:
Disclosed is a method for purifying a antibiotic from a crude or partially purified solution containing the lantibiotic. In preferred embodiments, the lantibiotic is nisin, although the common structural features of lantibiotics dictate the effectiveness of the disclosed purification methods for other members of the lantibiotic genus. The method includes the step of forming an incubation mixture comprising the solution containing the lantibiotic and a proteolytic enzyme, and incubating the mixture under conditions optimized for selective proteolytic activity.
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Inventors:
Coogulin, Lithiday Tay
Club, joseph h
Club, joseph h
Application Number:
JP2004543583A
Publication Date:
January 19, 2006
Filing Date:
October 07, 2003
Export Citation:
Assignee:
Imyusel corporation
International Classes:
C12P21/02; C07K14/315; C12N9/70; C12P21/04; C12S3/14
Domestic Patent References:
| JPH02265441A | 1990-10-30 | |||
| JPH06261691A | 1994-09-20 | |||
| JPH08238059A | 1996-09-17 | |||
| JPH09313110A | 1997-12-09 | |||
| JPH09313111A | 1997-12-09 | |||
| JPH1156250A | 1999-03-02 | |||
| JPH04126093A | 1992-04-27 |
Attorney, Agent or Firm:
Heikichi Odashima