Title:
REACTIVE HETEROCYCLE-SUBSTITUTED 7-HYDROXYCOUMARIN AND CONJUGATE THEREOF
Document Type and Number:
Japanese Patent JP2010254993
Kind Code:
A
Abstract:
To provide fluorescent chemical materials comprising reactive dyes and dye conjugates and uses thereof.
There are provided chemically active, water-soluble, heterocycle-substituted 7-hydroxycoumarin dyes, bioconjugates thereof and uses thereof. The conjugates obtained from the reactive heterocycle-substituted 7-hydroxycoumarin dyes are used for analyzing biological compounds by using a flow cytometer equipped with a violet laser as an excitation source due to their strong absorption at 405 nm and a high fluorescence quantum yield, and are particularly useful as fluorescent labels for reagents detecting biopolymers such as antibodies or nucleic acid probes.
Inventors:
DIWU ZHENJUN
DUBROVSKY TIMOTHY
ABRAMS BARNABY
LIAO JINFANG
MENG QINGLIN
DUBROVSKY TIMOTHY
ABRAMS BARNABY
LIAO JINFANG
MENG QINGLIN
Application Number:
JP2010085260A
Publication Date:
November 11, 2010
Filing Date:
April 01, 2010
Export Citation:
Assignee:
BECTON DICKINSON CO
International Classes:
C07D407/04; C09B57/02; C07D407/14; C07D409/04; C07D409/14; C07D417/04; C07D417/14; G01N33/533
Foreign References:
| DE3044128A1 | 1982-07-15 | |||
| DE3044128A1 | 1982-07-15 |
Other References:
JPN6014022020; Ｂｕｌｌｅｔｉｎ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ ｏｆ Ｊａｐａｎ Ｖｏｌ．５８， Ｎｏ．２, 1985, ｐ．７３１-４
JPN6014022020; Ｂｕｌｌｅｔｉｎ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ ｏｆ Ｊａｐａｎ Ｖｏｌ．５８， Ｎｏ．２, 1985, ｐ．７３１-４
JPN6014022020; Ｂｕｌｌｅｔｉｎ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ ｏｆ Ｊａｐａｎ Ｖｏｌ．５８， Ｎｏ．２, 1985, ｐ．７３１-４
Attorney, Agent or Firm:
Yoshikazu Tani
Kazuo Abe
Kazuo Abe
Previous Patent: FIBER-REINFORCED POLYAMIDE RESIN COMPOSITION
Next Patent: RESIN COMPOSITION AND MOLDED BODY THEREOF
Next Patent: RESIN COMPOSITION AND MOLDED BODY THEREOF