Title:
組換え酵母形質転換体及びこれを用いた免疫グロブリンFc断片の生産方法
Document Type and Number:
Japanese Patent JP6473696
Kind Code:
B2
Abstract:
The present invention relates to a transformant prepared by introducing an expression vector comprising a polynucleotide encoding for a human immunoglobulin Fc fragment into Pichia sp. yeast, a method for producing an immunoglobulin Fc fragment comprising culturing the transformant, and recovering the immunoglobulin Fc fragment from the culture, and an immunoglobulin Fc fragment, prepared by the above method for use as a drug carrier. The transformant is suggested as a solution to the problems associated with the use of E. coli or animal cells as hosts for producing immunoglobulin Fc fragments useful as drug carriers, so that it can find various applications in the effective and economical production of drugs.
Inventors:
Kim Jin Seung
Hoyoung
Ourim
Kim Min Young
Jun Seungyeop
Kwon Sechan
Hoyoung
Ourim
Kim Min Young
Jun Seungyeop
Kwon Sechan
Application Number:
JP2015555915A
Publication Date:
February 20, 2019
Filing Date:
February 03, 2014
Export Citation:
Assignee:
HANMI PHARMACEUTICAL CO., LTD.
International Classes:
C12N1/19; C12N15/13; C12N15/31; C12N15/62; C12N15/81; C12P21/02
Domestic Patent References:
| JP2009513110A | ||||
| JP2012531921A | ||||
| JP11000174A | ||||
| JP2007531513A |
Foreign References:
| CN1974601A |
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa