Title:
REDUCED NAPHTHALENE COMPOUNDS, MANUFACTURE AND MEDICINAL COMPOSITION CONTAINING THEM
Document Type and Number:
Japanese Patent JPS5758639
Kind Code:
A
Abstract:
A compound of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein: Ar is phenyl, optionally substituted by one or more C1-4 alkyl, C1-4 alkoxy, halogen, cyano, nitro, hydroxy, CONH2, CO2W wherein W is C1-6 alkyl or C1-4 alkylphenyl which phenyl may be substituted by one or more C1-4 alkyl, C1-4 alkoxy or halogen, NR1R2 wherein R1 and R2 are selected from hydrogen or C1-6 alkyl, NHCO C1-6 alkyl or C1-6 alkylcarbonyloxy; phenyl disubstituted on adjacent carbon atoms by methylenedioxy; furyl or thienyl; the dotted lines represent an optionally present double bond; and X is CO or CR1OH wherein R1 is hydrogen or C1-4 alkyl, having useful pharmacological activity, processes for their preparation and their use.
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Inventors:
AREKUSANDAA KUROTSUSAN GOODEI
JIYOSEFUIN MERII KOTSUKUSU
JIYOSEFUIN MERII KOTSUKUSU
Application Number:
JP12001681A
Publication Date:
April 08, 1982
Filing Date:
July 30, 1981
Export Citation:
Assignee:
BEECHAM GROUP LTD
International Classes:
C07C69/035; A61K31/12; A61K31/135; A61K31/165; A61K31/275; C07C45/00; C07C45/56; C07C45/67; C07C45/68; C07C49/623; C07C49/657; C07C49/683; C07C49/687; C07C49/697; C07C49/747; C07C49/753; C07C51/00; C07C65/32; C07C65/38; C07C67/00; C07C69/76; C07C201/00; C07C205/45; C07C225/22; C07C231/00; C07C231/12; C07C235/84; C07C253/00; C07C255/56; C07D307/46; C07D317/54; C07D333/22; C07D339/06; (IPC1-7): C07C45/68; C07C49/657; C07C49/687; C07C49/747; C07C49/753; C07C65/32; C07C69/035; C07C69/76; C07C79/36; C07C87/50; C07C97/10; C07C103/20; C07C121/76; C07D307/46; C07D317/50; C07D333/10