Title:
ヒト脳由来の新規カリウムチャネルタンパク質である、SLO2およびSLO4
Document Type and Number:
Japanese Patent JP2005507633
Kind Code:
A
Abstract:
The invention provides isolated nucleic acid and amino acid sequences of Slo2, a member of the Slo family of potassium channel proteins, also known as "maxi" or BK potassium channel proteins. Also provided herein are antibodies to Slo2, methods of detecting Slo2, methods of screening for potassium channel activators and inhibitors using biologically active Sl02, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2.
Inventors:
Jegra, Timothy James
Witzel, Julie Dixon
Witzel, Julie Dixon
Application Number:
JP2002543646A
Publication Date:
March 24, 2005
Filing Date:
August 15, 2001
Export Citation:
Assignee:
Aikagen Inc.
International Classes:
A61K45/00; A61P25/02; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07K14/47; C07K14/705; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12N15/63; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566; (IPC1-7): C12N15/09; A61K45/00; A61P25/02; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita