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Title:
SEPARATION AND PURIFICATION OF ASPARTAME AND ASPARTAME DERIVATIVE
Document Type and Number:
Japanese Patent JPH11171895
Kind Code:
A
Abstract:

To readily and efficiently separate and purify aspartame(APM) and N-[N(3,3-dimethylbutyl)-L-Cl-aspartyl]-L-phenylalanine methyl ester in high purity.

This method for separating and purifying APM and (3,3- dimethylbutyl)APM comprises passing an aqueous solution containing aspartame and N-[N-(3,3-dimethylbutyl)-L-α-aspartyl-L-phenylalanine methyl ester through a column in which nonpolar high porous polymer-based resin is packed and separating APM from N-(3,3-dimethylbutyl)-APM.


Inventors:
NAGASHIMA KAZUTAKA
KISHISHITA AKIHIRO
Application Number:
JP34093997A
Publication Date:
June 29, 1999
Filing Date:
December 11, 1997
Export Citation:
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Assignee:
AJINOMOTO KK
International Classes:
C07K1/16; A23L27/30; C07K5/072; C07K5/075; (IPC1-7): C07K5/072; C07K1/16