SERPENTINE TRANSMEMBRANE ANTIGEN EXPRESSED IN HUMAN PROSTATE CANCER AND METHOD FOR USING THE SAME

Title:

SERPENTINE TRANSMEMBRANE ANTIGEN EXPRESSED IN HUMAN PROSTATE CANCER AND METHOD FOR USING THE SAME

Document Type and Number:

Japanese Patent JP2006204290

Kind Code:

A

Abstract:

To provide a diagnosing and treating method useful in various kinds of cancers such as human prostate cancer.

A STEAP (Six Transmembrane Epithelial Antigen of the Prostate) protein and a polypeptide fragment thereof are created by using a STEAP gene encoding the STEAP exclusively or predominantly expressed in the prostate, as well as in prostate cancer or a complementary polynucleotide in a novel family of cell surface serpentine transmembrane antigens by a gene recombination technique. The antibody binding thereto is also created.

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Inventors:

AFAR DANIEL E H
HUBERT RENE S
RAITANO ARTHUR B
SAFFRAN DOUGLAS C
MITCHELL STEVE CHAPPELL
FARIS MARY
JAKOBOVITS AYA

Application Number:

JP2005365540A

Publication Date:

August 10, 2006

Filing Date:

December 19, 2005

Export Citation:

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Assignee:

AGENSYS INC

International Classes:

A01K67/027; A61K35/76; C12N15/09; A61K38/00; A61K39/00; A61K39/395; A61K48/00; A61K51/00; A61P13/08; A61P35/00; A61P43/00; C07K14/47; C07K14/705; C07K14/82; C07K16/18; C07K16/30; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/02; C12P21/02; C12P21/08; C12Q1/68; G01N33/566; G01N33/574

Attorney, Agent or Firm:

Hatsushi Shimizu
Koichi Niimi

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