Title:
STABLE CRYSTAL MODIFICATIONS OF DOTAP CHLORIDE
Document Type and Number:
Japanese Patent JP2018203776
Kind Code:
A
Abstract:
To provide crystal modifications of DOTAP chloride excellent in stability, suitable for the preparation of pharmaceutical compositions.SOLUTION: The present invention relates to crystal modifications of racemic (2R,S)- and enantiomerically pure (2R)- and (2S)-DOTAP chloride, to processes for the preparation thereof, and to the use thereof for the preparation of pharmaceutical compositions.SELECTED DRAWING: None
Inventors:
MICHAEL WILHELM PLATSCHER
ALFRED HEDINGER
ALFRED HEDINGER
Application Number:
JP2018178658A
Publication Date:
December 27, 2018
Filing Date:
September 25, 2018
Export Citation:
Assignee:
MERCK PATENT GMBH
International Classes:
C07C219/08; A61K9/127; A61K45/00; A61K47/18; A61P17/00; A61P43/00; C07C213/10
Attorney, Agent or Firm:
Akio Miyazaki
Masaaki Ogata
Masaaki Ogata