Title:
抗原性ヘテロ複合体を含む安定な免疫原性産物
Document Type and Number:
Japanese Patent JP4698223
Kind Code:
B2
Abstract:
Stable immunogenic product (A) for inducing antibodies (Ab) directed against one or more antigenic proteins (I) in a subject comprises immunogneic heterocomplexes of (I) and protein carriers (II), where less than 40% of (I) is covalently linked to (II). An Independent claim is also included for a method for preparing (A).
Inventors:
Le Boneck, Helen
Zagre, Daniel
Zagre, Daniel
Application Number:
JP2004535614A
Publication Date:
June 08, 2011
Filing Date:
September 16, 2003
Export Citation:
Assignee:
Neovac
International Classes:
A61K39/385; A61K38/00; A61K38/18; A61K38/19; A61K39/00; A61K39/12; A61K39/21; A61K39/35; A61K39/39; A61K47/48; A61P31/18; A61P35/00; A61P37/08; C07K14/52; C07K19/00; A61K
Domestic Patent References:
| JP11501310A |
Foreign References:
| WO2002011759A1 |
Other References:
KIM,S.K. et al,Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines,Vaccine,1999年,Vol.18, No.7-8,p.597-603
Attorney, Agent or Firm:
Takashi Koshiba