Title:
STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE HMG-COA REDUCTASE INHIBITORS
Document Type and Number:
Japanese Patent JP2015078238
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To solve the following problem: although the most preferred agents used in the prior art to stabilize pharmaceutical compositions comprising HMG-CoA reductase inhibitors are the inorganic carbonate and bicarbonate salts, the use of alkaline agents in these formulations can cause problems for patients taking the pharmaceutical composition, particularly for patients with a damaged gastric mucous membrane.SOLUTION: The present invention relates to stable pharmaceutical compositions comprising one or more HMG-CoA reductase inhibitors, a method for preparing the stable compositions and uses for the compositions. The stable pharmaceutical compositions of the invention may be used, in particular, for the treatment of hyperlipoproteinemia and atherosclerosis.
Inventors:
TIMOTHY STANLEY
ISABEL DELGADO
ESTELA LLORENS
EVA MUNOZ
ISABEL DELGADO
ESTELA LLORENS
EVA MUNOZ
Application Number:
JP2015012348A
Publication Date:
April 23, 2015
Filing Date:
January 26, 2015
Export Citation:
Assignee:
GENERICS UK LTD
International Classes:
A61K45/00; A61K9/20; A61K9/48; A61K31/22; A61K31/366; A61K31/40; A61K31/404; A61K31/4418; A61K31/505; A61K47/32; A61K47/36; A61P9/10; A61P43/00
Domestic Patent References:
| JP2003055217A | 2003-02-26 | |||
| JP2002284680A | 2002-10-03 | |||
| JP2009527577A | 2009-07-30 |
Foreign References:
| WO2004071402A2 | 2004-08-26 | |||
| WO2007100822A2 | 2007-09-07 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Shinya Mitsuhiro
Previous Patent: SUBSTITUTED HYDROXAMIC ACID AND USE THEREOF
Next Patent: ALKYL HYDROPEROXIDE COMPOUND PRODUCTION METHOD
Next Patent: ALKYL HYDROPEROXIDE COMPOUND PRODUCTION METHOD