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Title:
STEROID AS AGONIST FOR FXR
Document Type and Number:
Japanese Patent JP2007269815
Kind Code:
A
Abstract:

To provide a compound useful as an agonist for FXR (Farsnesoid X receptor), a preparation containing such the compound, and use thereof on the therapy.

The compound useful as the agonist to the FXR is a compound of formula (I) (wherein, R is ethyl, propyl or allyl), and a pharmaceutically acceptable salt, a solvate or an amino acid conjugate thereof.

COPYRIGHT: (C)2008,JPO&INPIT


Inventors:
PELLICCIARI ROBERTO
Application Number:
JP2007162928A
Publication Date:
October 18, 2007
Filing Date:
June 20, 2007
Export Citation:
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Assignee:
INTERCEPT PHARMACEUTICALS INC
International Classes:
A61K47/18; C07J9/00; A61K31/56; A61K31/575; A61K31/58; A61K47/20; A61K51/00; A61P1/16; A61P3/06; A61P9/10; A61P43/00; C07J43/00; C07J75/00
Domestic Patent References:
JPH02292300A1990-12-03
JPH01135795A1989-05-29
JP4021327B
Foreign References:
WO2000037077A12000-06-29
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata