Title:
SUBSTITUTED ARYL THIOUREA, RELATED COMPOUND AND INHIBITOR FOR VIRAL REPLICATION
Document Type and Number:
Japanese Patent JP2007084548
Kind Code:
A
Abstract:
To provide a method of treating patients suffering from certain infectious diseases.
Specific acyl thiourea derivatives have potent antiviral activity. The compounds of the derivatives are a potent and/or selective inhibitor of Hepatitis C virus replication. The patients suffering from the certain diseases, can be treated with administration of a pharmaceutical composition comprising at least one of the same compounds, their salts, solvates or acylated prodrugs and at least one of a pharmaceutically acceptable carrier, excipient or diluent. The infectious diseases involve viral infection, more particular, HCV infection.
Inventors:
CHEN DAWEI
DESHPANDE MILIND
THURKAUF ANDREW
PHADKE AVINASH
WANG XIANGZHU
SHEN YIPING
LIU CUIXIAN
QUINN JESSE
OHKANDA JUNKO
LI SHOUMING
DESHPANDE MILIND
THURKAUF ANDREW
PHADKE AVINASH
WANG XIANGZHU
SHEN YIPING
LIU CUIXIAN
QUINN JESSE
OHKANDA JUNKO
LI SHOUMING
Application Number:
JP2006272359A
Publication Date:
April 05, 2007
Filing Date:
October 03, 2006
Export Citation:
Assignee:
ACHILLION PHARMACEUTICALS INC
International Classes:
C07C335/26; A61K31/24; A61K31/40; A61K31/445; A61K31/55; A61P1/16; A61P31/12; C07D207/16; C07D207/34; C07D209/42; C07D209/48; C07D211/62; C07D211/70; C07D211/86; C07D213/65; C07D213/81; C07D215/06; C07D215/38; C07D215/48; C07D217/04; C07D217/14; C07D231/14; C07D233/42; C07D233/90; C07D239/26; C07D241/24; C07D241/44; C07D249/06; C07D257/04; C07D261/18; C07D263/34; C07D263/56; C07D271/08; C07D271/12; C07D277/56; C07D277/62; C07D277/66; C07D277/68; C07D285/06; C07D295/04; C07D295/135; C07D295/14; C07D295/15; C07D307/52; C07D307/68; C07D307/85; C07D311/24; C07D311/66; C07D317/68; C07D319/20; C07D333/20; C07D333/34; C07D333/70; C07D401/04; C07D405/12; C07D407/12; C07D409/12; C07D413/12; C07D417/04; C07D417/12; C07D487/04; C07D495/04; A61K31/17; A61K31/245; A61K31/277; A61K31/341; A61K31/343; A61K31/352; A61K31/357; A61K31/36; A61K31/381; A61K31/401; A61K31/4035; A61K31/404; A61K31/41; A61K31/415; A61K31/4162; A61K31/4164; A61K31/4192; A61K31/42; A61K31/422; A61K31/423; A61K31/4245; A61K31/427; A61K31/428; A61K31/433; A61K31/437; A61K31/44; A61K31/4406; A61K31/443; A61K31/4439; A61K31/4453; A61K31/4525; A61K31/47; A61K31/472; A61K31/4965; A61K31/498; A61K31/519; A61K31/5375
Domestic Patent References:
| JPS51125323A | 1976-11-01 | |||
| JPS5143742A | 1976-04-14 | |||
| JPS61122263A | 1986-06-10 | |||
| JPH07206811A | 1995-08-08 | |||
| JP2005537230A | 2005-12-08 | |||
| JP4206382B2 | 2009-01-07 |
Attorney, Agent or Firm:
Takeshi Oshio
Previous Patent: USE OF FUNGAL IMMUNOMODULATORY PROTEIN
Next Patent: INTERMEDIATE FOR PRODUCTION OF NEW TRIAZOLO(4,5-D)PYRIMIDINE COMPOUND
Next Patent: INTERMEDIATE FOR PRODUCTION OF NEW TRIAZOLO(4,5-D)PYRIMIDINE COMPOUND