Title:
ムスカリン性Ｍ１受容体ポジティブアロステリックモジュレーターとしての置換アザ環
Document Type and Number:
Japanese Patent JP7034284
Kind Code:
B2
Abstract:
The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the methods of preparation, pharmaceutical composition, combinations and the use of compound formula (I), their stereoisomers, isotopic forms or pharmaceutically acceptable salts thereof.
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Inventors:
Ramakrishna Nilogi
Anil Calvary Cinde
Abdul Rashid Mohammed
Rajesh Kumar Badange
Ragava Choudari Paracharla
Venkateswir Justy
Anil Calvary Cinde
Abdul Rashid Mohammed
Rajesh Kumar Badange
Ragava Choudari Paracharla
Venkateswir Justy
Application Number:
JP2020528300A
Publication Date:
March 11, 2022
Filing Date:
November 21, 2018
Export Citation:
Assignee:
SUVEN LIFE SCIENCES LIMITED
International Classes:
C07D471/04; A61K31/13; A61K31/27; A61K31/437; A61K31/4375; A61K31/444; A61K31/445; A61K31/4545; A61K31/473; A61K31/55; A61K45/00; A61P25/04; A61P25/18; A61P25/20; A61P25/28; A61P29/02; A61P43/00
Domestic Patent References:
| JP2017513894A |
Foreign References:
| WO2015163485A1 | ||||
| WO2012158475A1 | ||||
| WO2012003147A1 | ||||
| WO2013063549A1 |
Other References:
DAVOREN, J. E. et al.,Journal of Medicinal Chemistry,2017年,Vol. 60,pp. 6649-6663
MISTRY, S. N. et al.,ACS Chemical Neuroscience,2016年,Vol. 7,pp. 647-661
MISTRY, S. N. et al.,ACS Chemical Neuroscience,2016年,Vol. 7,pp. 647-661
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe