Title:
置換ブテンアミド医薬組成物及びその製造方法
Document Type and Number:
Japanese Patent JP7356119
Kind Code:
B2
Abstract:
The invention belongs to the field of pharmaceutical preparations, and relates to a substituted crotonamide pharmaceutical composition and a preparation method thereof. The pharmaceutical composition comprises 5 parts to 50 parts of (E)-N-(3-cyano-7-ethoxy-4-(3-ethynylphenylamino)quinoline-6-yl)-4-(dimethylamino)butyl-2-enamide maleate, 40 parts to 120 parts of filler, 2 parts to 20 parts of disintegrant, 0 part to 6 parts of adhesive, and 0.5 part to 5 parts of lubricant. The filler is selected from a carbohydrate. The pharmaceutical composition has the beneficial effects of good quality stability and suitability for large-scale production.
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Inventors:
Tang Kaito
王 ▲ベイ▼
Kuzama
Kudzu Kaito
Wang Zhengjun
王 ▲ベイ▼
Kuzama
Kudzu Kaito
Wang Zhengjun
Application Number:
JP2022531443A
Publication Date:
October 04, 2023
Filing Date:
November 26, 2020
Export Citation:
Assignee:
Suzhong Pharmaceutical Group Co., Ltd.
Jiangsu Suzhou Traditional Chinese Medicine Research Institute Co., Ltd.
Jiangsu Suzhou Traditional Chinese Medicine Research Institute Co., Ltd.
International Classes:
A61K31/4706; A61K9/48; A61K47/14; A61K47/26; A61K47/36; A61K47/38; A61P35/00
Domestic Patent References:
| JP2012531433A |
Foreign References:
| CN104513200A |
Attorney, Agent or Firm:
Mitsuru Kimura
Yasushi Morikawa
Kei Sakurada
Hideki Mie
Yasushi Morikawa
Kei Sakurada
Hideki Mie
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