Title:
置換カルボン酸類
Document Type and Number:
Japanese Patent JP2006525329
Kind Code:
A
Abstract:
The present invention relates to compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
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Inventors:
Fan Xand, Michael, Shee.
White House, Darren
Combs, Kelly
Fu, Xiao Jin
White House, Darren
Combs, Kelly
Fu, Xiao Jin
Application Number:
JP2006509981A
Publication Date:
November 09, 2006
Filing Date:
April 14, 2004
Export Citation:
Assignee:
The Institute for Pharmaceutical Discovery, LRC
International Classes:
C07D209/08; A61K31/216; A61K31/343; A61K31/405; A61P3/10; A61P25/00; A61P35/00; A61P43/00; C07C69/736; C07D263/57; C07D277/66; C07D307/79; C07D307/80; C07D307/81; C07D307/91; C07D307/92; C07D405/10; C07D417/04; C07D471/04; C07D263/56
Domestic Patent References:
| JP2002514635A | 2002-05-21 | |||
| JPH10509146A | 1998-09-08 |
Foreign References:
| US6232322B1 | 2001-05-15 | |||
| US20020077347A1 | 2002-06-20 | |||
| GB1176339B | ||||
| GB1249492B | ||||
| US3755603A | 1973-08-28 | |||
| US5886022A | 1999-03-23 |
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda