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Title:
SUBSTITUTED QUINOLINE DERIVATIVE, ITS PREPARATION AND USE THEREOF
Document Type and Number:
Japanese Patent JPH0859621
Kind Code:
A
Abstract:

To obtain a substituted quinoline derivative used as a medicament useful as an antiviral agent, especially a therapeutic agent for AIDS.

This compound is represented by formula II [(n) is 0-4; R1 is a halogen, CF3, OH, an alkyl, an alkoxy, an alkylthio, NO2, NH2, CN, phenyl, phenoxy or the like; X is O, S, Se, NR2 or N-O-R2; R2 is H, an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an alkylcarbonyl, an aryl, an arylcarbonyl or the like; R5 and R6 are each H, carboxyl, an alkyl, an alkenyl, a cycloalkyl, an alkylcarbonyl, an aryl, a heteroaryl or the like; R3 and R4 are each H, an alkyl, an alkenyl, a cycloalkyl, a cycloalkenyl, an aryl, an arylalkyl, a heteroaryl or the like], e.g. E-4-n-butylene-6-chloro-3,4-dihydro-3,3-dimethylquinolin-2(1H)-one.


Inventors:
RAINHARUTO KIRUSHIYU
IERUKUUPEETAA KURAIMU
GIYUNTAA RIISU
MANFUREETO REESUNAA
IRUBUIN BUINKURAA
Application Number:
JP22863995A
Publication Date:
March 05, 1996
Filing Date:
August 15, 1995
Export Citation:
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Assignee:
HOECHST AG
International Classes:
A61K31/47; A61P31/12; A61P31/18; C07D215/22; C07D215/227; C07D215/24; C07D215/26; C07D215/36; C07D215/38; C07D215/58; C07D221/20; C07D401/06; C07D401/12; C07D401/14; (IPC1-7): C07D215/22; A61K31/47; C07D215/36; C07D215/38
Attorney, Agent or Firm:
Chika Takagi (2 outside)