Title:
Substitution amino imidazo Pyridazine
Document Type and Number:
Japanese Patent JP6073868
Kind Code:
B2
Abstract:
The present invention relates to substituted aminoimidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Inventors:
Knut Ice
Florian Purler
Ludwig Zorn
Arne Scholz
Philip Linau
Marc Yan Gnaud
Wolf Boehmer
Judith Gunter
Jörg van Haener
Daniel Corr
Florian Purler
Ludwig Zorn
Arne Scholz
Philip Linau
Marc Yan Gnaud
Wolf Boehmer
Judith Gunter
Jörg van Haener
Daniel Corr
Application Number:
JP2014513164A
Publication Date:
February 01, 2017
Filing Date:
May 30, 2012
Export Citation:
Assignee:
Bayer Intellectual Property GmbH
International Classes:
C07D487/04; A61K31/5025; A61K45/00; A61P1/00; A61P11/00; A61P13/00; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07D519/00
Domestic Patent References:
| JP2010502716A | ||||
| JP2009506993A | ||||
| JP2009532407A | ||||
| JP2009502734A | ||||
| JP2009541268A | ||||
| JP2009541241A |
Foreign References:
| WO2008025822A1 |
Other References:
Oyarzabal J. et al.,Discovery of Mitogen-Activated Protein Kinase-Interacting Kinase 1 Inhibitors by a Comprehensive Fragment-Oriented Virtual Screening Approach,J. Med. Chem.,2010年,Vol.53,pp.6618-6628
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe
Previous Patent: Mass spectrograph variable outlet opening
Next Patent: TRANSFER TYPE COLOR RECORDING SYSTEM
Next Patent: TRANSFER TYPE COLOR RECORDING SYSTEM