Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
SYNTHESIS OF A-RING SYNTHON OF 19-NOR-1-ALFA, 25- DIHYDROXYVITAMIN D3 FROM (D)-GLUCOSE
Document Type and Number:
Japanese Patent JP2003176250
Kind Code:
A
Abstract:

To provide a method of synthesizing phosphine oxide being a synthon for ring A used for preparing 19-nor-vitamin D compound and provide a new synthetic intermediate that is formed on the way of the synthetic route.

In this new synthetic process, the phosphine oxide is prepared from (D)-glucose.


Inventors:
Deluca, Hector F.
Shimizu, Masato
Yamada, Sachiko
Application Number:
JP2002000220721
Publication Date:
June 24, 2003
Filing Date:
July 30, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION
International Classes:
C07C43/196; C07C45/29; C07C45/60; C07C49/753; C07F7/18; C07F9/53; C07H3/02; C07H9/04; (IPC1-7): C07C43/196; C07C49/753; C07F7/18; C07F9/53
Foreign References:
Other References:
JPN6009046245, Noriaki IWASE et al., "Substrate Specificity of 2−Deoxy−scyllo−inosose Synthase, the Starter Enzyme for 2−Deoxystreptamine", Biosci. Biotechnol. Biochem., 1998, Vol.62, No.12, p.2396−2407
Attorney, Agent or Firm:
社本 一夫 (外5名)