Title:
Synthesis method
Document Type and Number:
Japanese Patent JP6335936
Kind Code:
B2
Abstract:
Described is a method of synthesizing 6-(5-ethoxyhept-1-yl)bicyclo[3.3.0] octan-3-one by reacting 3-(5-ethoxyhept-1-yl) cyclopentene with dichloroketene. The resulting reaction products are reacted with acetic acid and zinc to produce 4-(5-ethoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 4-(5-ethoxyhept-1-yl)bicyclo [3.2.0]heptan-7-one, which are reacted with trimethylsulfonium iodide to produce 2-(5-ethoxyhept-1-yl)spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] and 4-(5-ethoxyhept-1-yl)spiro-[bicyclo-[3.2.0]heptane-6,2'-oxirane]. Lithium iodide is reacted with 2-(5-ethoxyhept-1-yl)spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] and 4-(5-ethoxyhept-1-yl)spiro-[bicyclo-[3.2.0]heptane-6,2'-oxirane] to produce 6-(5-ethoxyhept-1-yl)bicyclo[3.3.0]octan-3-one. A method of synthesizing 6-(5-methoxyhept-1-yl)bicyclo[3.3.0]octan-3-one is also described.
Inventors:
Van Wittenberg, Jimmy
La Croix, Rene
La Croix, Rene
Application Number:
JP2015562340A
Publication Date:
May 30, 2018
Filing Date:
March 11, 2013
Export Citation:
Assignee:
BCS BUSINESS CONSULTING SERVICES PTE LTD.
International Classes:
C07C45/58; C07C49/517
Domestic Patent References:
| JP61500550A |
Foreign References:
| US4731458 |
Other References:
人名反応に学ぶ有機合成戦略,(株)化学同人,2007年,第2刷,第102-103頁
Attorney, Agent or Firm:
Iseki Katsumori
Shuhei Kaneko
Shuhei Kaneko
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