Title:
TABLET OF TEMOCAPRIL HYDROCHLORIDE WITH EXCELLENT PRESERVATION STABILITY
Document Type and Number:
Japanese Patent JP2009091292
Kind Code:
A
Abstract:
To provide a tablet of temocapril hydrochloride stable at a high temperature and high humidity comprising combination of temocapril hydrochloride which is a principal ingredient, with other adjuvants such as a vehicle, a binder, a disintegrant, a lubricant, etc.
The tablet of temocapril hydrochloride consisting of the temocapril hydrochloride as the principal ingredient, a stearic acid and/or L-leucine as a lubricant, lactose or D-mannitol as a preferable vehicle, hydroxypropyl cellulose as a binder, and a low substituted hydroxypropyl cellulose as a disintegrant, is stable at a high temperature and high humidity.
Inventors:
NOZAWA KENJI
OKAMURA YASUSHI
NAKATANI AKITOSHI
FUJIWARA NAHOKO
OKAMURA YASUSHI
NAKATANI AKITOSHI
FUJIWARA NAHOKO
Application Number:
JP2007263034A
Publication Date:
April 30, 2009
Filing Date:
October 09, 2007
Export Citation:
Assignee:
SAWAI SEIYAKU KK
International Classes:
A61K31/554; A61K9/20; A61K47/10; A61K47/12; A61K47/18; A61K47/38; A61P9/12
Domestic Patent References:
| JPS63225322A | 1988-09-20 | |||
| JP2002516881A | 2002-06-11 |
Attorney, Agent or Firm:
Yoshitaka Tani