Title:
【発明の名称】3-(1,2-ベンズイソキサゾール-3-イル)-4-ピリジンアミンおよび誘導体
Document Type and Number:
Japanese Patent JP3057829
Kind Code:
B2
Abstract:
3-(1,2-Benzisoxazol-3-yl)-4-pyridinamines and derivatives This invention relates to 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines of the formula where R1 is hydrogen, loweralkyl, arylalkyl or acyl; R2 is hydrogen, loweralkyl or arylalkyl, X is hydrogen, halogen, nitro or amino; or the pharmaceutically acceptable addition salts thereof, and where applicable, the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention are useful as analgesics, for alleviating various memory dysfunctions characterized by a decreased cholinergic function, as cognition enhancers in the treatment of senile dementia such as Alzheimer's disease and as topical antiinflammatory agents for the treatment of various dermatoses.
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Inventors:
J. Joseph Thomas Klein
Richard Yards Fland
Richard Yards Fland
Application Number:
JP20171391A
Publication Date:
July 04, 2000
Filing Date:
August 12, 1991
Export Citation:
Assignee:
Hoechst Marion Roussel Incorporated
International Classes:
A61K31/423; A61K31/4427; A61K31/4439; A61P17/00; A61P25/04; A61P25/28; A61K31/44; A61P29/00; C07D213/75; C07D261/20; C07D413/04; (IPC1-7): C07D413/04; A61K31/4439; A61P17/00; A61P25/04; A61P25/28
Attorney, Agent or Firm:
Chika Takagi (2 outside)