Title:
【発明の名称】ACE-2阻害化合物及びその使用方法
Document Type and Number:
Japanese Patent JP2002543120
Kind Code:
A
Abstract:
ACE-2 inhibiting compounds are disclosed. These compounds include compounds of formula (IV):wherein the variables are as described in the specification. Pharmaceutical compositions containing the compounds are also discussed. The pharmaceutical compositions may contain an effective amount of a compound of the invention to treat ACE-2 associated disorders such as a blood pressure related disease or disorder, cell proliferation disorder, kidney disorder, kinetensin associated disorder, inflammation associated disorder, or an allergic disorder.
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Inventors:
Acton Susan El
Ocaine timothy dee
Gould Alexandra Yi
Dulles Natalie A
Guam Bing
Brown james a
Ocaine timothy dee
Gould Alexandra Yi
Dulles Natalie A
Guam Bing
Brown james a
Application Number:
JP2000614989A
Publication Date:
December 17, 2002
Filing Date:
April 28, 2000
Export Citation:
Assignee:
Millennium Pharmaceuticals, Inc.
International Classes:
A61K31/198; A61K31/341; A61K31/381; A61K31/405; A61K31/415; A61K31/4164; A61K31/426; A61K31/4402; A61K31/4406; A61P1/00; A61P1/02; A61P5/30; A61P9/00; A61P9/02; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P17/00; A61P19/02; A61P21/00; A61P25/04; A61P29/00; A61P37/08; A61P43/00; C07C229/16; C07C229/24; C07C229/26; C07C229/36; C07C271/20; C07C275/24; C07C323/52; C07C323/58; C07D209/20; C07D233/64; C07D213/55; C07D231/12; C07D233/54; C07D235/16; C07D249/08; C07D261/08; C07D277/06; C07D277/20; C07D277/30; C07D277/40; C07D277/42; C07D307/54; C07D333/24; C07D405/06; C07D413/04; (IPC1-7): C07D233/64; A61K31/198; A61K31/341; A61K31/381; A61K31/405; A61K31/415; A61K31/4164; A61K31/426; A61K31/4402; A61K31/4406; A61P1/00; A61P1/02; A61P5/30; A61P9/00; A61P9/02; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P17/00; A61P19/02; A61P21/00; A61P25/04; A61P29/00; A61P37/08; A61P43/00; C07C229/26; C07D209/20; C07D213/55; C07D231/12; C07D277/30; C07D307/54; C07D333/24; C07D413/04
Attorney, Agent or Firm:
Tsutomu Kanakubo